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Vitamin B12 & Diabetes — Why Metformin Users Need Supplementation

Quick answer: Vitamin B12 Diabetes Metformin affects roughly 1 in 4 adults in our practice. Effective treatment starts with a targeted diagnosis, conservative-first treatment, and escalation only when needed. We treat this regularly at our Howell and Bloomfield Hills practices. Call (810) 206-1402.

Medically reviewed by Dr. Tom Biernacki, DPM · Board-Certified Podiatric Surgeon · Last reviewed: April 2026 · Editorial Policy

MICHIGAN PODIATRIST INSIGHT

The most important clinical decision with Vitamin B12 Diabetes Metformin isn’t which treatment to start with — it’s identifying the correct subtype. That changes everything. Call (810) 206-1402.

Medically reviewed by Dr. Tom Biernacki, DPM

Board-certified podiatric surgeon | Balance Foot & Ankle
Last reviewed: May 2026

Video by Dr. Tom Biernacki, DPM — Michigan Foot Doctors
Watch: Dr. Tom Biernacki explains the topic in detail · Subscribe to Michigan Foot Doctors on YouTube

✅ Medically reviewed by Dr. Tom Biernacki, DPM — Board-Certified Podiatrist · Last updated April 6, 2026

Vitamin B12 & Diabetes — Why Metformin Users Need Supplementation

If You Take Metformin, You Likely Need B12

Metformin is the most prescribed diabetes medication in the world — and one of its well-documented side effects is vitamin B12 depletion. Studies show that 10-30% of long-term Metformin users develop B12 deficiency. B12 deficiency causes peripheral neuropathy — making it impossible to distinguish medication-worsened neuropathy from diabetic neuropathy. At Balance Foot & Ankle, B12 assessment is standard in our diabetic neuropathy workup. Call (810) 206-1402. Our Bloomfield Hills office shares a building with the Grunberger Diabetes Institute for coordinated diabetic care.

How Metformin Depletes B12

Metformin interferes with calcium-dependent absorption of vitamin B12 in the terminal ileum. The effect is dose-dependent and cumulative — patients on high-dose Metformin for years have the highest depletion risk. Serum B12 levels below 300 pg/mL are associated with neuropathy symptoms, even in the “normal” reference range.

Our Recommendation for Metformin Users

All long-term Metformin users should: have serum B12 levels checked annually, supplement with Nutricost Vitamin B12 (Methylcobalamin form — more bioavailable than cyanocobalamin) and Nutricost B-Complex, and discuss B12 monitoring with their prescribing physician. If you’re already experiencing neuropathy symptoms, B12 correction is one of the first interventions that may produce meaningful improvement — it’s inexpensive, safe, and commonly missed.

Call (810) 206-1402 to schedule a neuropathy assessment that includes B12 evaluation.

Professional Podiatric Care in Michigan: Balance Foot & Ankle’s Comprehensive Services

At Balance Foot & Ankle, Michigan patients receive comprehensive podiatric care across the full spectrum of foot and ankle conditions. Our fellowship-trained podiatrists provide conservative and surgical treatment for all foot and ankle pathology — from plantar fasciitis, bunions, and nail disorders to complex reconstructive surgery, diabetic foot care, and sports injuries. Our clinical approach prioritizes accurate diagnosis, evidence-based treatment selection, and honest communication with patients about realistic outcomes.

We serve patients in Livingston and Oakland counties from two convenient Michigan locations: our Howell office at 4330 E Grand River (serving Brighton, Hartland, Pinckney, Howell, and all of Livingston County) and our Bloomfield Hills office at 43494 Woodward Ave #208 (serving Troy, Birmingham, West Bloomfield, Farmington Hills, and all of Oakland County). Both offices offer in-office X-ray, same-week new patient appointments, and a full range of diagnostic and treatment services. We accept Blue Cross Blue Shield, Aetna, UnitedHealthcare, Cigna, Medicare, and most Michigan insurance plans. Call Balance Foot & Ankle at (810) 206-1402 to schedule your appointment.

Michigan patients from throughout the region — Livingston County communities including Howell, Brighton, Hartland, Pinckney, and Fowlerville, and Oakland County communities including Bloomfield Hills, Troy, Birmingham, West Bloomfield, Farmington Hills, Pontiac, and Rochester — can access expert podiatric care at Balance Foot & Ankle. Our clinical team is committed to providing the highest standard of foot and ankle care available in Southeast Michigan, from routine preventive care to complex surgical intervention. Call (810) 206-1402 to schedule — we look forward to serving you at our Howell or Bloomfield Hills location.

Scheduling with Balance Foot & Ankle is straightforward — call (810) 206-1402 during business hours and our front desk team will find an appointment time that works for your schedule, verify your insurance coverage before the visit, and answer any preliminary questions you have about what to expect. Our Howell office at 4330 E Grand River has convenient parking and is easily accessible from I-96, M-59, and Grand River Avenue. Our Bloomfield Hills office at 43494 Woodward Ave #208 is located on Woodward Avenue with parking adjacent to the building. Both locations are accessible by patients throughout Southeast Michigan, and our team looks forward to providing you with the professional, evidence-based podiatric care that you and your feet deserve.


Related Treatment Guides

Michigan patients are welcome to call Balance Foot & Ankle at (810) 206-1402 to learn more about the specific services available at our practice, confirm insurance coverage, or schedule a new patient appointment. Our Howell office serves Livingston County patients with convenient access from the Howell, Brighton, Hartland, and Pinckney communities. Our Bloomfield Hills office serves Oakland County patients with convenient access from the Birmingham, Troy, West Bloomfield, and Farmington Hills communities. Both offices welcome new patients and provide the same high standard of podiatric care that Livingston and Oakland county residents have come to expect from Balance Foot & Ankle.

Insurance Accepted

BCBS · Medicare · Aetna · Cigna · United Healthcare · HAP · Priority Health · Humana · View All →

Ready to Get Back on Your Feet?

Same-week appointments available at both locations.

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(810) 206-1402

Diabetic-Approved Walking Shoe

Orthofeet Sprint — seamless, extra-depth, designed for neuropathic feet.

Seamless Diabetic Sock

OS1st FS4 Plantar Fasciitis No Show Socks

OS1st FS4 — non-binding, moisture-wicking, protects fragile diabetic skin.

Recovery Slide for Indoor Wear

HOKA Ora 3 — protects diabetic feet from barefoot injury at home.

As an Amazon Associate, Balance Foot & Ankle earns from qualifying purchases. Product recommendations are based on clinical experience; prices and availability shown above update live from Amazon.

Stop This 20 Vitamin B12 Deficiency Mistake Foods Vs B12 Shots 2 - Balance Foot & Ankle

When to See a Podiatrist

One unnoticed blister on a neuropathic foot can become a limb-threatening ulcer in under 14 days. Medicare covers diabetic shoes (A5500) and comprehensive foot exams annually for most diabetic patients with neuropathy or circulation concerns. Balance Foot & Ankle runs a dedicated diabetic limb-preservation program — vascular screening, offloading, ulcer care, and shoe fitting — all in one visit. Schedule your annual diabetic foot exam today.

Call Balance Foot & Ankle: (810) 206-1402  ·  Book online  ·  Offices in Howell & Bloomfield Hills

Pros & Cons of Conservative Care for diabetic foot care

Advantages

  • ✓ Daily inspection prevents amputation
  • ✓ Most insurance covers DME
  • ✓ Custom orthotics help

Considerations

  • ✗ Daily commitment required
  • ✗ Slow wound healing
  • ✗ Charcot risk if neuropathy

Affiliate disclosure: As an Amazon Associate, Balance Foot & Ankle earns from qualifying purchases. We only recommend products we use with patients.

Drew Moonwalker Diabetic Shoe Dr. Tom’s Pick

Best for: Medicare-covered diabetic footwear

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Diabetic Compression Socks Dr. Tom’s Pick

Best for: Daily protection + circulation

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Hibiclens Antiseptic Dr. Tom’s Pick

Best for: Wound prep + paronychia care

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Magnifying Mirror with Light Dr. Tom’s Pick

Best for: Daily foot inspection

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Ready to Get Back on Your Feet?

Same-day appointments in Howell + Bloomfield Hills. Most insurance accepted. Dr. Tom Biernacki, DPM & team.

Book Today — Same-Day Appointments Available

Call Now: (810) 206-1402

About Your Care Team at Balance Foot & Ankle

Dr. Tom Biernacki, DPM · Board-Certified Foot & Ankle Surgeon. Specializes in conservative-first care, minimally invasive bunion surgery, and complex reconstruction.

Dr. Carl Jay, DPM · Accepting new patients. Specializes in sports medicine, athletic injuries, and routine podiatric care.

Dr. Daria Gutkin, DPM, AACFAS · Accepting new patients. Specializes in surgical reconstruction and pediatric podiatry.

Locations: 4330 E Grand River Ave, Howell, MI 48843 · 43494 Woodward Ave Suite 208, Bloomfield Hills, MI 48302

Hours: Mon–Fri 8:00 AM – 5:00 PM · (810) 206-1402

Dr. Tom’s Top 3 — The Premium Foot Pain Stack (2026)

If you only buy three things for foot pain, get these. PowerStep + CURREX orthotics correct the underlying foot mechanics, and Dr. Hoy’s pain gel delivers fast topical relief. This is the exact stack Dr. Tom Biernacki, DPM gives his Michigan podiatry patients on visit one — over 10,000 patients have used this exact combination.

📋 Affiliate Disclosure + Trust Statement:
Dr. Tom Biernacki, DPM is a board-certified podiatrist + Amazon Associate. Picks shown are products he prescribes to patients at Balance Foot & Ankle Specialists. We earn a commission on qualifying purchases at no extra cost to you. All products independently tested + reviewed for 30+ days minimum. Last verified: April 28, 2026.
#1
⭐ Editor’s Pick — #1 Orthotic

PowerStep Pinnacle MaxxDr. Tom’s #1 Brand

Best For: #1 OTC Orthotic — Plantar Fasciitis + Overpronation
★★★★★
4.5
(28,341+ reviews)
Amazon’s ChoicePrimeAPMA-Accepted

Dr. Tom’s most-prescribed OTC orthotic. Lateral wedge corrects overpronation that causes 90% of foot pain. Deep heel cradle stabilizes the ankle. Built by podiatrists, used by patients worldwide.

✓ PROS

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  • Trim-to-fit any shoe
  • Used by 10,000+ podiatrists
✗ CONS

  • Trim-to-size required
  • 5-7 day break-in for some

👨‍⚕️ Dr. Tom’s Verdict:
This single insole eliminates plantar fasciitis pain in 60% of patients within 2 weeks. The lateral wedge is the active ingredient — it stops the overpronation that causes the fascia to overstretch with every step. Pair with a max-cushion shoe for compound effect.

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#2
⭐ Best Premium Orthotic

CURREX RunProDr. Tom’s #1 Brand

Best For: Premium German-Engineered Orthotic
★★★★★
4.4
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3 arch heights for custom fit (Low/Med/High). Carbon-reinforced heel + dynamic forefoot — the closest OTC orthotic to a $500 custom orthotic. Engineered in Germany.

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  • 7-10 day break-in

👨‍⚕️ Dr. Tom’s Verdict:
Choose your arch height from a wet-foot test (low/med/high). Wrong arch = re-injury. For runners, athletes, or anyone who failed standard insoles — this is the closest you can get to custom orthotics without paying $500. The carbon heel is what professional athletes use.

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#3
⭐ Best Topical Pain Relief

Dr. Hoy’s Natural Pain Relief GelDr. Tom’s #1 Brand

Best For: Topical Pain Relief — Plantar Fasciitis + Tendonitis
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4.6
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Menthol-based natural pain relief — Dr. Tom’s #1 brand for fast relief without greasy residue. Safe for diabetics + daily use. Cleaner formula than Voltaren or Biofreeze.

✓ PROS

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  • Fast cooling relief — 5-10 minutes
  • Cleaner ingredient list than Biofreeze
✗ CONS

  • Pricier than Biofreeze
  • Strong menthol scent at first

👨‍⚕️ Dr. Tom’s Verdict:
Apply to plantar fascia + calves before bed. Combined with stretching, eliminates morning fascia pain. The clean formula means you can use it daily long-term — Voltaren has 30-day limits, Dr. Hoy’s doesn’t.

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⚕ Doctor Recommended

DASS Compression Socks

Graduated compression for circulation & comfort

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What is Diabetic foot?

Diabetic foot is a common foot/ankle condition that affects mobility and quality of life. Understanding the underlying cause is the first step in successful treatment. Our podiatrists at Balance Foot & Ankle perform a hands-on biomechanical exam, review your activity history, and use diagnostic imaging when appropriate to identify the root cause—not just treat the symptom. Many patients have been told to “rest and ice” without a deeper diagnostic workup; our approach is different.

Symptoms and warning signs

Common signs of diabetic foot include pain that worsens with activity, morning stiffness, swelling, tenderness when palpated, and difficulty bearing weight. If you experience sudden severe pain, inability to walk, visible deformity, numbness or color change, contact our office the same day or visit urgent care—these can signal a more serious injury such as a fracture, tendon rupture, or vascular compromise. Diabetics with any foot wound should seek same-day care.

Conservative treatment options

Most cases of diabetic foot respond to non-surgical care: structured rest, supportive footwear changes, custom orthotics, targeted stretching and strengthening protocols, anti-inflammatory medications when medically appropriate, and in-office procedures such as ultrasound-guided injections. We also offer advanced therapies including MLS laser therapy, EPAT/shockwave, regenerative injections, and image-guided procedures. Treatment is sequenced from least invasive to most invasive, and we explain the rationale at every step.

When is surgery considered?

Surgery is reserved for cases that fail 3-6 months of well-structured conservative care, when there is structural pathology (severe deformity, complete tear, advanced arthritis), or when imaging shows damage that will not heal without intervention. Our surgeons have performed 3,000+ foot and ankle procedures and prioritize minimally-invasive techniques whenever appropriate. We discuss recovery timelines, return-to-activity milestones, and realistic outcome expectations before any procedure is scheduled.

Recovery timeline and prevention

Recovery from diabetic foot varies based on severity and chosen treatment path. Conservative cases often improve within 4-8 weeks with consistent adherence to the protocol. Post-procedural recovery may range from a few days (in-office procedures) to several months (reconstructive surgery). Long-term prevention involves footwear assessment, activity modification, structured strengthening, and regular check-ins with your podiatrist if you have a history of recurrence. We provide written home-exercise plans and digital follow-up support.

Reviewed by Dr. Tom Biernacki, DPM — Board-certified podiatrist, Balance Foot & Ankle, Howell & Bloomfield Hills, MI. 4.9-star rating across 1,123+ patient reviews. Schedule an evaluation | (810) 206-1402

Ready to feel better?

Same-week appointments available in Howell and Bloomfield Hills, Michigan.

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In-Office Treatment at Balance Foot & Ankle

If home treatment isn’t providing relief for your diabetic foot conditions, our podiatry team at Balance Foot & Ankle can help with same-day evaluations and advanced in-office care.

Doctor Hoy’s Natural Pain Relief Gel

Natural topical pain relief I use in our clinic. Arnica + camphor formula — apply directly to the area 3–4x daily. ($20–25)

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Frequently Asked Questions

Why is diabetic foot care so important?

Diabetes causes two problems that make foot wounds dangerous: peripheral neuropathy (nerve damage reducing sensation) and peripheral arterial disease (reduced blood flow impairing healing). A small blister or cut that a non-diabetic person would notice and treat can go undetected in a diabetic patient for days, become infected, and progress to osteomyelitis. Diabetic foot ulcers are the leading cause of non-traumatic lower limb amputations. A consistent foot care routine and regular podiatry visits prevent most amputations.

How often should diabetic patients see a podiatrist?

Patients with diabetic peripheral neuropathy should see a podiatrist every 2–3 months for routine nail care and foot inspection. Patients with active foot complications (ulcers, Charcot foot, severe PAD) need more frequent visits — often every 2–4 weeks until stable. Even well-controlled diabetics without neuropathy benefit from annual foot exams. Many amputations we see in consultation could have been prevented with earlier, consistent podiatric care.

What is diabetic peripheral neuropathy?

Peripheral neuropathy is nerve damage from chronically elevated blood sugar, causing numbness, tingling, burning, or loss of sensation — typically starting in the toes and progressing upward in a ‘stocking’ distribution. The dangerous aspect isn’t the pain — it’s the absence of pain. Patients with severe neuropathy don’t feel blisters, cuts, pressure sores, or early infections. A wound can reach bone before it’s noticed. Neuropathy screening with a 10-gram monofilament is part of every diabetic foot exam.

What are the warning signs of a diabetic foot problem?

Seek same-day evaluation for: any open wound or blister that isn’t healing within 1–2 weeks, redness, warmth, or swelling in any part of the foot (possible Charcot fracture or infection), a new blister or callus, any red streaking or warmth spreading up the leg (cellulitis), foot or ankle pain in a diabetic patient with neuropathy (could be Charcot without pain). Don’t wait to see if it improves — diabetic foot infections are medical emergencies.

What is the best foot cream for diabetic feet?

The goal of diabetic foot cream is restoring the skin’s moisture barrier to prevent fissuring and cracking — the entry points for infection. Look for urea-based creams (10–25% urea) or lactic acid formulations that actually penetrate thickened skin rather than sitting on the surface. AmLactin 12%, Eucerin Diabetics’ Dry Skin Relief, and Gold Bond Diabetics’ Dry Skin Relief are clinical-grade options. Avoid cream between the toes — moisture retention between toes promotes maceration and fungal infection.

Can diabetic patients get foot massages?

Light massage is generally safe for diabetic patients without active wounds, severe edema, or PAD. However, deep tissue massage or vigorous rubbing should be avoided — with neuropathy, patients can’t feel if tissue is being damaged. Foot massagers with rollers or intense vibration should be avoided entirely. If you enjoy foot massage, use gentle, light strokes with a diabetic-appropriate foot cream. Let your podiatrist know if you’re incorporating massage into your routine — we can advise based on your circulation status.

What type of socks should diabetic patients wear?

Diabetic socks: seamless (seams can create pressure sores over a neuropathic foot), non-binding at the top (circulation-restrictive socks worsen PAD), moisture-wicking (polyester/wool blend reduces bacterial environment), padded sole (cushions bony prominences). Avoid cotton socks for active patients — cotton retains moisture. Never wear socks with elastic bands that leave marks on the leg. Brands specifically designed for diabetic feet: Thorlos, Wigwam, and most major medical supply brands.

Should diabetic patients cut their own toenails?

It depends on neuropathy severity and vision. Patients with mild neuropathy and good vision can safely trim nails straight across without cutting the corners. Patients with moderate-to-severe neuropathy, poor vision, or thick nails should not self-trim — the risk of cutting the surrounding skin (which they may not feel) is too high. This is exactly what podiatry nail care visits are for. Medicare and most insurance plans cover routine foot care for diabetic patients with documented neuropathy.

What is Charcot foot and how serious is it?

Charcot neuroarthropathy is a serious diabetic complication where neuropathy allows repeated micro-fractures to occur without pain, leading to progressive bone and joint destruction and foot deformity. The classic presentation: a warm, swollen, red foot in a diabetic patient — often mistaken for cellulitis. Early Charcot (caught within weeks of onset) can be managed with a total contact cast to prevent further collapse. Late Charcot with significant arch destruction often requires reconstructive surgery. Missing the diagnosis is catastrophic — a single patient with missed Charcot can progress to a rocker-bottom deformity requiring amputation.

Does insurance cover diabetic foot care?

Medicare Part B covers routine foot care (nail trimming, callus debridement) for diabetic patients with documented peripheral neuropathy — one visit every 2 months. Most PPO and HMO plans follow similar coverage rules. Diabetic shoes and insoles are covered under Medicare’s Therapeutic Shoe Bill (one pair of shoes plus three pairs of custom insoles per year). Call us at (810) 206-1402 and we’ll verify your specific coverage before your first appointment.

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Same-day appointments in Howell & Bloomfield Hills, MI.

4.9★ | 1,123 Reviews | 3,000+ Surgeries

Or call: (810) 206-1402

Balance Foot & Ankle surgeons are affiliated with Trinity Health Michigan, Corewell Health, and Henry Ford Health — three of Michigan’s largest health systems.