What is Grierson Gopalan Syndrome? [Causes & How to Treat IT!]

How is Grierson Gopalan Syndrome treated? We go over medications, home remedies, Vitamin B12 for burning feet and leg pain!

grierson gopalan syndrome treatment

What is Grierson Gopalan Syndrome?

  • Grierson Gopalan Syndrome is also known as burning feet syndrome. The pain and he from burning feet syndrome can become more painful at night.
  • It usually involves the bottom of the feet, but also can involve the top of the foot, the ankle and even the legs.
  • There is some overlap between Grierson Gopalan Syndrome and peripheral neuropathy.

Is there a Cure for Grierson Gopalan Syndrome?

  • Nerve pain can be extremely difficult to quantify and objectively measure.
  • This means that there are no specific definitions of what this disease is. As podiatrists nerve pain is one of the most common and one of the most varied problems that we see.
  • We usually have the success significantly improving the pain.
  • But it may be difficult to completely eliminate it unless the patient is somehow able to get completely healthy which unfortunately is rare as we all age.


Burning Feet and Leg Syndrome Treatment Video:

This video is specific toward peripheral neuropathy, but the same treatment options can be overlapped onto Grierson Gopalan Syndrome.

We also go over Grierson Gopalan Syndrome home remedies and how to treat it.

Grierson Gopalan Syndrome Symptoms:

  • Grierson go plan syndrome is also known as burning feet syndrome. It is usually recognized by symptoms in which the foot becomes very uncomfortable.
  • This usually happens when someone is sitting on the couch or in bed in the foot becomes hot and painful. The burning sensation can become more intense at night, but feel better during the day especially while the blood flow is moving.
  • The symptoms can range from hardly anything to very severe pain and burning.
  • There is very little scholarly articles on Grierson Gopalan Syndrome.
  • In some cases the bottom of the foot and the heel could form pain at the bottom of the foot, whereas in other cases it can extend all the way up the feet the ankles and the legs.

Specific symptoms:

  • Pins and needles sensation in the skin.
  • You can feel like prickling or tingling.
  • The skin can turn red.
  • The skin can feel extremely warm.
  • The feet can feel tired and very heavy.
  • There can be a sharp shooting or stabbing pain.
  • You could develop a form of numbness in the feet or even extend up into the ankles and the legs.
  • The heat and burning is usually worse at nighttime.


Grierson Gopalan Syndrome Causes:

Other Conditions that Cause or are Associated with Burning Sensations of the Feet

Chronic diabetes and elevated blood sugar can eventually lead to a condition called diabetic peripheral neuropathy. This can eventually cause nerve pain as well as numbness burning and tingling.

Hyperthyroidism can be associated with peripheral neuropathy as well, there is some overlap between burning feet and warm feet and hyperthyroidism.

Morton’s Neuroma:
A Morton’s neuroma is a condition where there is a thickening and constriction of the nerve in her foot.

This most commonly occurs in the third webs pace between the third and fourth toes.

Rheumatoid arthritis:
Rheumatoid arthritis is not immune disease that can cause onset of pain especially in her hands and her feet.

This is not quite nerve pain, but it can lead to nerve pain.

Gout is also not immune condition where there is a buildup of crystals in your joints. This usually happens in your big toe joint.

This is called uric acid.

We go over a great treatment guide regarding this.

Vitamin B deficiency:
Vitamin B deficiencies can be linked to peripheral neuropathy and nerve pain. Specifically vitamin B12 can be associated with pain.

Athlete’s foot:
Athlete’s foot can cause redness to develop on the skin.

This can cause burning numbness and tingling. This would be a simple condition to evaluate for. This is more of a skin condition the nerve condition. But it can cause significant nerve pain.

Foot nerve entrapment:
Foot nerve entrapments are very common.

We see Baxter’s nerve entrapment. We also see tarsal tunnel nerve pain and we also see Morton’s neuroma nerve pain. There are many more nerve pains but these are the 3 most common once we see.

how to treat grierson gopalan syndrome

Grierson Gopalan Syndrome Diagnosis:

Nerve pain and burning feet syndrome can be extremely difficult to objectively measure. There is no agreed-upon set of criteria or threshold that will determine this nerve disease.
For this reason you have to work with your podiatrist or neurologist to determine the exact extent of your symptoms and how much treatment you want to pursue.
These are standard diagnosis guidelines below:

Historical examination your podiatrist:

Your podiatrist will go over your goals and what your symptoms are.

Physical examination:

Your podiatrist will test how sensitive your skin is as well as any changes in reflexes were neurological function. It is important to rule out any other problems that could be causing foot pain. In our experience this is where we can make the most difference. There are many correctable problems beyond nerve pain that we uncovered. In our experience this is the most common way we can help and we routinely expect to see improvement.

Blood tests:

It is always a good idea to check a complete blood count to rule out any abnormalities in your blood serum or electrolytes. It is a good idea to check your vitamin D, your vitamin B12 your potassium sodium and chloride levels as well as your magnesium.
There is also a good idea to check your blood sugar level.

Nerve function testing:

This is usually not done by us as podiatrists, but in our opinion it is not frequently necessary to be done. We do work with a team of neurologists to perform electromyography and nerve conduction velocity testing. In advanced disease that is not improving with more straightforward testing this may be necessary.

Grierson Gopalan Syndrome Pictures:

Grierson Gopalan Syndrome Medication:

  • Historically vitamin B12 has been very effective treatment option for peripheral neuropathy and nerve symptoms in the feet.
  • A comprehensive daily can be very effective regarding nutrient deficiencies such as B12.
  • There is no specific evidence for Grierson Gopalin Syndrome and vitamin B12, but in general this does have some overlap with peripheral neuropathy pain.
  • Studies do show that incorporating vitamin B as well as vitamin B12 in your daily multivitamin can show some benefit in preventing peripheral nerve disease.
  • Just be aware that there is no specific studies linking Grierson Gopalan Syndrome and vitamin B12.

Grierson Gopalan Syndrome Vitamin B12:

  • There is strong research that Vitamin B12 can be effective for nerve disease and peripheral neuropathy.
  • While not completely proven, there is probably some benefit in taking vitamin b12 for Grierson Gopalan Syndrome.
  • Always check with your podiatrist for your own personal use.


Nerve Medication:

  • There are nerve medication options like gabapentin or lyrica.
  • We recommend talking with your podiatrist or doctor regarding these options.
  • They can be very effective but these are considered prescription controlled substances.


Pain Medication:

  • Pain medication such as narcotic medications can be very  effective as well.
grierson gopalan syndrome pictures

Grierson Gopalan Syndrome Treatment:

Home Remedies & Prevention Options:

These are strong prevention options to think about that can practically reduce your nerve pain.

Contact dermatitis:

  • It is common to have red and burning sensations in the feet secondary to an allergic reaction to socks or shoe material.
  • We see is very commonly with sweating.
  • We recommend patients sometimes change the materials in there is socks and there shoes.
  • Sometimes a contact dermatitis reaction can cause numbness and burning and tingling pain.

Smoking and arterial disease:

Smoking can eventually lead to peripheral arterial disease.

  • Peripheral arterial disease can lead to a condition called claudication.
  • This means pain with walking or even resting at night this means the blood flow cannot fight gravity and reach your toes thus the tips of your toes can ache at nighttime.
  • At our office we will work with vascular surgery department and we can evaluate patient’s blood flow in an objective manner.

Moist conditions with rubbing:

  • We frequently see numbness burning and tingling in the feet secondary due to sweaty socks and sweaty feet.
  • If you feet are standing and rubbing all day and socks that are not very supportive this can cause skin conditions as well as numbness burning and tingling to the feet.

Get Better Socks:

  • Sometimes bad sock material can cause issues to the nerve skin and foot skin.
  • We recommend socks that are specifically built for handling sweat.
  • We give some length to good socks!

Hot sweaty feet:

  • There is a foot condition and hand condition called hyperhidrosis.
  • These types of conditions can lead to dermatitis of the skin. Eczema and dermatitis mean inflammation of the skin.
  • Sweat can do this.
  • The best thing to do is to identify what is causing her skin to sweat.
  • It is possible to use antiperspirant’s but it is probably better idea to wear breathable shoes and breathable socks first.
  • Checkout are recommended shoe guide for good shoes and socks.

Irritating fabrics:

  • Test different materials for your socks and shoes.
  • Sometimes switching to a synthetic material or synthetic sock can make all the difference.
  • Sometimes switching to a new pair of shoes that is higher-quality can lead to a lot of relief.

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